Manganese can affect oxidative enzymes systems whose integrity is needed to continue to supply the energy required for the degradation and synthesis of the various chemical compounds that function in nerve transmission.
Manganese makes nerve and brain matter more alkaline. Manganese is an alkaline element, but it acts more upon the nerve cells and upon the cells of the brain. It increases the oxidation in the cells of nerve and brain matter.
Manganese activates substances essential to the well-being of the brain and nerves. The brain needs manganese-activated choline and ATP to make acetylcholine, a chemical compound that causes muscle action by transmitting nerve impulses.
Acetylcholine encourages human body to discharge norepinephrine and epinephrine, those important hormones that help human to cope with fears and anger.
Another of manganese’s work sites in the neurological system is in the synthesis of dopamine, which helps nerves transmit messages.
Toxicity from an overload of manganese in the brain causes a depletion of dopamine. The first symptoms of manganese overload are fatigue, hypnotic-like state or trance, irritability and erratic behavior that has been euphemistically labeled by toxicologist as ‘manganese madness’.
Low levels of manganese can contribute to infertility, bone malformation, weakness and seizures.
Maintenance of nerves and brain by manganese
